Cardiovascular diseases account for most NCD deaths, or 17.5 million people annually, according to the WHO.
The GACD funds research into prevention and treatment of Hypertension on low- and middle-income countries. Hypertension, also known as high or raised blood pressure, is a condition in which the blood vessels have persistently raised pressure, putting them under increased stress. Each time the heart beats; it pumps blood into the vessels, which carry the blood throughout the body. Blood pressure is created by the force of blood pushing against the walls of blood vessels (arteries) as the heart pumps it. The higher the pressure, the harder the heart has to pump.
In nearly all high-income countries, widespread diagnosis and treatment with low-cost medication have led to a significant drop in the proportion of people with raised blood pressure, as well as the average blood pressure across populations – and this has contributed to a reduction in deaths from heart disease. For example, the prevalence of raised blood pressure in the WHO region of the Americas in 2014 was 18%, as compared to 31% in 1980.
In contrast, low-income countries have the highest prevalence of raised blood pressure. In the WHO African region, more than 30% of adults in many countries are estimated to have high blood pressure and this proportion is increasing. Furthermore, the average blood pressure levels in this region are much higher than global averages.
Many people with high blood pressure in developing countries are not aware of their disease, and do not have access to treatments that could control their blood pressure and significantly reduce their risk of death and disability from heart disease and stroke. Detection, treatment and control of hypertension is an important health priority worldwide.
Globally, increased blood pressure is the leading cause of deaths and disability. An estimated 18% of deaths (9.4 million) and 162 million years of life lost were attributed to increased blood pressure in 2010. One half of blood pressure related disease occurs in people with higher levels of blood pressure even within the normal range. Hypertension now disproportionately impacts low and middle-income countries.
Source – WHO, World Hypertension League
GACD funded research
- HT01 - Utilizing HIV/AIDS infrastructure as a gateway to chronic care of hypertension in Africa
- HT02 - Developing an innovative strategy for hypertension detection, treatment and control in two middle income countries (Hypertension Outcomes Prevention and Evaluation: HOPE-4)
- HT03 - DREAM-GLOBAL: Diagnosing hypeRtension - Engaging Action and Management in Getting LOwer Bp in Aboriginal and LMIC
- HT04 - A school-based education programme to reduce salt intake in children and their families
- HT05 - Treating hypertension in rural South Africa: Strengthening community-based outreach services for integrated chronic care
- HT06 - Improving the control of hypertension in rural India: Overcoming the barriers to diagnosis and effective treatment
- HT07 - A smartphone-based clinical decision support system for primary health care workers in rural India
- HT08 - Randomised Controlled Trial of early use of a simplified treatment regimen incorporating a half-dose, three-in-one blood pressure lowering pill vs. usual care for improving hypertension control in India
- HT09 - Developing a national salt reduction program for India
- HT10 - Cost effectiveness of salt reduction interventions in Pacific Islands
- HT11 - Launching a salt substitute to reduce blood pressure at the population level
- HT12 - Task Shifting and Blood Pressure Control in Ghana: A Cluster-Randomized Trial
- HT13 - Optimizing Linkage and Retention to Hypertension Care in Rural Kenya
- HT14 - Comprehensive Approach for Hypertension Prevention and Control in Argentina
- HT15 - Tailored Hospital-based Risk Reduction to Impede Vascular Events after Stroke (THRIVES)