Lung Diseases LD09, 2017 – 2017

Lung function of Chinese adults and the predictive value of peak flow rate to long-term incidence and prognosis of lung diseases

Funding amount

$2.5 million

Background

Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) has been the leading cause of morbidity and mortality in China. This high burden of chronic lung diseases may be due to increasing exposure to risk factors, but also to a lacking of population-based screening, poor early diagnosis and management, particularly in rural areas of China. The risk status for COPD in Chinese population is poorly understood, and large variations might be expected between urban and rural areas. Recent reports suggest that peak expiratory flow (PEF) measurements may be an inexpensive way of screening and initial identification of severe cases of COPD for subsequent confirmatory spirometry. But there are limited studies assess the predictive value of PEF to lung diseases. Therefore, we sought to investigate epidemic status of lung functions and risk for COPD across China, and to clarify the predictive value of PEF to the incidence and prognosis of chronic lung diseases.

Objectives

To describe the status of lung functions and evaluate the risk for COPD, information about lung diseases and related symptoms were collected by the standard questionnaire in this study. During the screening, PEF was measured using unified device. It’s measured three times for each participant, and the maximum value was recorded. Incidence of COPD and other lung diseases were also recorded.

Until this September, we have recruited about 1 million participants from 16 provinces. And this study will recruit 1.5 million participants from 31 provinces at the end of June 2017.

Principal Investigator

Jiapeng Lu, National Center for Cardiovascular Diseases, China

Funding organisations

  • Lung Diseases LD09
  • China
  • 2017 – 2017