Chronic lung disease is a mounting health priority for Vietnam, with over 10% of the population suffering from either COPD or asthma (1, 2), and three out of every four adult males having a history of smoking (3). Evidence-based interventions to prevent (4) and reduce the burden of chronic obstructive lung disease (OLD) (5) are well-established internationally, however such strategies currently reach only a small proportion of the most vulnerable populations in this resource-limited setting. Furthermore, a lack of local evidence has deterred policy-makers from applying these approaches (6).
Aims & objectives
(A) To determine the effect of a smoking cessation intervention upon the rate of sustained abstinence among smokers after two years; (B) To evaluate the effectiveness of an integrated SC and ICS intervention upon the proportion of individuals with one or more exacerbations of COPD or asthma within two years of follow-up;
- To determine the effect of the combined intervention upon all-cause mortality
- To determine physician and patient compliance with a structured clinical decision algorithm for patients with persistent and/or recurrent respiratory symptoms.
- To conduct a cost-effectiveness analysis of smoking cessation among smokers, and the combined intervention among patients with OLD.
- To evaluate the knowledge, attitudes and beliefs of patients and health care workers regarding smoking cessation and ICS use before and after the intervention.
- To disseminate findings: engaging local and national policy-makers in translating the established protocols into practice and policy.
- Lam HT, Ekerljung L, NF TFSTN, et al. Prevalence of COPD by disease severity in men and women in northern Vietnam. COPD. 2014;11(5):575-81.
- Lim S, et al. Impact of chronic obstructive pulmonary disease in the Asia-Pacific region: the EPIC Asia population-based survey. Asia Pac Fam Med. 2015;14(1):4.
- Bui TV, Blizzard L, Luong KN, et al. Declining Prevalence of Tobacco Smoking in Vietnam. Nicotine tobacco research. 2015 Jul;17(7):831-8.
- Willemse BW, et al. The impact of smoking cessation on respiratory symptoms, lung function, airway hyperresponsiveness and inflammation. Eur Respir J. 2004;23(3):464-76.
- Yang IA, Clarke MS, Sim EH, et al. Inhaled corticosteroids for stable chronic obstructive pulmonary disease. Cochrane DB Syst Rev. 2012;7:CD002991.
- Higashi H, Khuong TA, Ngo AD, et al. Evidence and decision making: tobacco control policy and legislation in Vietnam. Int J Health Plan M. 2013 Jan-Mar;28(1):e72-94.
Gregory Fox, University of Sydney, Australia
- National Health and Medical Research Council, Australia