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PRESCRIP-TEC: Prevention and screening Innovation Project – Towards Elimination of Cervical Cancer

Bangladesh, India, Slovakia, Uganda

PRESCRIP-TEC conducts implementation research in four countries over three continents, to investigate the feasibility of the new WHO guidelines for prevention and screening for cervical cancer. We will improve existing screening protocols in the four countries.

Background

We will improve interactive information with communities via traditional media, mobile devices and social media. At this moment, in most hard-to-reach areas women are approached through radio, face-to-face meetings, flyers, posters, etc. This results in limited uptake of cervical cancer screening in many populations.

Project plan

We will offer client-friendly HPV self-tests at home. Women do not have to travel to a clinic for gynaecological examination, to know if they have a HPV infection. Only those women who are HPV positive will be invited for further investigation.

In India, Bangladesh and Uganda HPV positive women will undergo a Visual Inspection of the cervix with Acetic acid (VIA) in mobile clinics or primary healthcare facilities, to diagnose any precancerous lesions, which need treatment. We will use an artificial intelligence decision support systems (AI-DSS) in gynaecological examination. We will offer to women who need treatment for precancerous lesions direct treatment in the location where the VIA is performed.

We will analyse the uptake of cervical cancer screening offered. Will improved communication lead to higher attendance? Will convenient HPV testing at home lead to higher acceptance? Will AI-DSS lead to better diagnosis?
We will perform a cost-effectiveness analysis and a produce a business case for the global introduction of hrHPV testing as routine screening for cervical cancer.

Publications and output

You can also visit the PRESCRIP-TEC project website for more information.

This project has a related case study Assessing the WHO strategy to eliminate Cervical Cancer: Insights from the PRESCRIP-TEC Project.

Principal investigators

  • Jaap Koot University of Groningen, Netherlands

  • Jelle Stekelenburg University of Groningen, Netherlands

Team members

  • Hanneke Vervoort University of Groningen, Netherlands

  • Janine de Zeeuw University of Groningen, Netherlands

  • Jerica van Niekerk Female Cancer Program Foundation, Netherlands

  • Marlieke de Fouw Female Cancer Program Foundation, Netherlands

  • Jogchum Beltman Female Cancer Program Foundation, Netherlands

  • Freek van Slooten Female Cancer Program Foundation, Netherlands

  • Jessica Vet Female Cancer Program Foundation, Netherlands

  • Heather Cubie University of Edinburgh, United Kingdom

  • Christine Campbell University of Edinburgh, United Kingdom

  • Aminur Rahman International Centre For Diarrhoeal Disease Research, Bangladesh

  • Anika Rahman International Centre For Diarrhoeal Disease Research, Bangladesh

  • Jaya Sankar, International Centre For Diarrhoeal Disease Research, Bangladesh

  • Naheed Nazrul Friendship, Bangladesh

  • Mosamat Umma Kulsum Friendship, Bangladesh

  • Arathi P Rao Manipal Academy of Higher Education, India

  • Shyamala Guruvare Manipal Academy of Higher Education, India

  • Keerthana Prasad Manipal Academy of Higher Education, India

  • Mamatha K. V. Sri Dharmasthala Manjunatheshwara College, India

  • Vidya Ballal Sri Dharmasthala Manjunatheshwara College, India

  • Arpana Sri Dharmasthala Manjunatheshwara College, India

  • Sharmila Pimple Tata Memorial Hospital, India

  • Gauravi Mishra Tata Memorial Hospital, India

  • Nasrin Banu Sikkim Manipal Institute of Medical Sciences, India

  • Pesona Grace Lucksom Sikkim Manipal Institute of Medical Sciences, India

  • Shamim Namagembe Uganda Rural Development and Training, Uganda

  • Carolyn Nakisige Uganda Cancer Institute, Uganda

  • Catherine Amuge Uganda Cancer Institute, Uganda

  • Christine Namulindwa Uganda Cancer Institute, Uganda

  • Johnblack Kabukye Uganda Cancer Institute, Uganda

  • Darina Sedláková League Against Cancer Slovakia, Slovakia

  • Táňa Grauzelová Healthy Regions, Slovakia

  • Marek Majdan Trnava University, Slovakia

  • Martin Rusnák Trnava University, Slovakia

  • Juliana Melichová Trnava University, Slovakia

  • Dominika Plancikova Trnava University, Slovakia

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