Sustainability determinants of an intervention to identify clinical deterioration and improve childhood cancer survival in low-resource hospitals

Background

Background and Goal. More than 90% of children with cancer live in low-resourced settings, where survival is only 20%. Sustainable evidence-based (EB) interventions yielding ongoing beneficial patient outcomes is critical to improve childhood cancer survival. A better understanding of factors promoting intervention sustainability in these settings is urgently needed. The goal of our project is to provide an empirical understanding of how clinical capacity, or the resources needed to sustain an intervention, impacts sustainment of a Pediatric Early Warning System (PEWS), EB interventions that improves pediatric oncology outcomes in low-resource hospitals by quickly detecting clinical deterioration in children with cancer, preventing the need for more intense treatment. Aims and Methods: We will conduct a prospective, longitudinal study of 92 low-resource hospitals implementing and sustaining PEWS.

This work will build on an ongoing St. Jude-Wash U Implementation Science Collaborative and Proyecto EVAT, a quality improvement collaborative of Latin American pediatric oncology centers.

Aims

Background and Goal. More than 90% of children with cancer live in low-resourced settings, where survival is only 20%. Sustainable evidence-based (EB) interventions yielding ongoing beneficial patient outcomes is critical to improve childhood cancer survival. A better understanding of factors promoting intervention sustainability in these settings is urgently needed. The goal of our project is to provide an empirical understanding of how clinical capacity, or the resources needed to sustain an intervention, impacts sustainment of a Pediatric Early Warning System (PEWS), EB interventions that improves pediatric oncology outcomes in low-resource hospitals by quickly detecting clinical deterioration in children with cancer, preventing the need for more intense treatment. Aims and Methods: We will conduct a prospective, longitudinal study of 92 low-resource hospitals implementing and sustaining PEWS.

This work will build on an ongoing St. Jude-Wash U Implementation Science Collaborative and Proyecto EVAT, a quality improvement collaborative of Latin American pediatric oncology centers.

Principal investigators

Team members

Funding organisations

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