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Genomic analysis of drug-resistant tuberculosis in sputum samples

Background

Tuberculosis(TB) is one of the most important infectious diseases globally. We need rapid molecular tests that can establish resistance profiles of this bacterium. Common tests only detect the most common genetic variants that cause resistance.

Aims

This project tested targeted sequencing (TS) from clinical sputum samples to detect a signature of genetic markers that could be linked to specific drug resistance.

Principal investigators

  • Francisco Xavier Soberon National Institute of Genomic Medicine, Mexico

Team members

  • Martín Barbosa-Amezcua National Institute of Genomic Medicine, Mexico

  • Vanessa González-Covarrubias National Institute of Genomic Medicine, Mexico

Funding organisations

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